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‏إظهار الرسائل ذات التسميات autism vaccine war. إظهار كافة الرسائل
‏إظهار الرسائل ذات التسميات autism vaccine war. إظهار كافة الرسائل

Autism Vaccine War: Is Scientific Inquiry Being Suppressed?



Dr. Beatrice Golomb's presentation This Is Your Brain On Politics pulls no punches in its critique of conflicts of interest, bias, censorship and intimidation involving pharmaceutical companies, health authorities and academic institutions and publications.  Professor Golomb's presentation includes commentary on pressure tactics, including intimidation, used by some pharmaceutical industry representatives to silence criticism of their products and the research that accompanies them.

Professor Golomb's presentation provides an interesting framework with which to consider the continued pressures exerted on Dr. Andrew Wakefield over an article he wrote in 1998 for which, in 2011, he was denounced, by journalistic decree,  as being guilty of fraud.  A refutation of the Wakefield fraud allegations by research microbiologist David Lewis was published in the BMJ  but has not received the major US or world media attention that the original fraud allegations attracted.

An even more recent  demonstration of pressure on those who question or study issues pertaining to vaccine safety has arisen in response to an article on vaccine adjuvants published by two UBC Ph.D.'s.  In Tom Sandborn's article in the Vancouver Courier Responses to UBC vaccine paper a problem for free scientific inquiry and expression UBC researchers raise questions, experience backlash Sandborn describes what appears to be an effort to suppress publication of peer reviewed journal articles which raise potential vaccine health issues. None other than Dr. Paul Offit is reported to have weighed in with comments which appear to suggest that studies or articles criticizing vaccine safety in any way should not be published:

"Shaw, who is on faculty at UBC with the Departments of Ophthalmology and Visual Sciences and Experimental Medicine and the Graduate Program in Neuroscience, and his colleague Lucija Tomljenovic have recently published a carefully parsed and thoroughly peer reviewed paper on vaccine safety, without a doubt one of the most controversial topics in medicine today. Despite the cautious and professional tone of the paper, and despite the authors' clear statement that their findings are not in themselves decisive, only pointing to the need for more extensive research into vaccine safety, the paper, published in November 2011 in the Journal of Inorganic Biochemistry which describes correlations and possible causal links between increased exposure to aluminum salts used as adjuvants in vaccines and increased levels of neurological trouble in exposed populations, seems to inflame angry and punitive responses in some quarters.


For example, when I discussed the Tomljenovic/Shaw paper with Dr. Paul Offit, a professor at the University of Pennsylvania, a strong proponent of vaccines and the developer of a successful new vaccine that has made him a multi-millionaire, he told me that the paper "should never have been published," despite the fact it was rigorously peer reviewed before publication. (Like many who want to insist that all questions of vaccine safety have been settled, Offit invokes the notorious Andrew Wakefield affair involving a now discredited and withdrawn paper published in The Lancet in 1998, which suggested a link between MMR vaccines and autism. Offit claims that paper is responsible for avoidable deaths as worried parents failed to vaccinate their children. Wakefield has recently filed a suit for defamation against Brian Deer, the investigative journalist whose work was central to the storm of criticism that surrounded the Lancet paper.)"

In the context of the autism vaccine war the late Dr. Bernadine Healy expressed confidence in the general safety of vaccines while talking about the need to explore possible vaccine impacts on susceptible populations. She also expressed confidence in public understanding of the value and importance of vaccines in protecting and promoting pubic health and safety while cautioning public health authorities against dismissing further scientific research on autism vaccine issues:

"There is a completely expressed concern that they don't want to pursue a hypothesis because that hypothesis could be damaging to the public health community at large by scaring people. First of all, I think the public's smarter than that. The public values vaccines. But more importantly, I don't think you should ever turn your back on any scientific hypothesis because you're afraid of what it might show."

The concerns expressed by Dr. Healy about the suppression of scientific inquiry into vaccine autism issues by public health authorities appear to be supported by the attempts to suppress the publication of articles like that of the UBC professors published after rigorous peer review which pointed to possible issues with aluminum salt adjuvants in vaccines.  Dr. Offit, and others who wish to suppress such inquiry, claim to be afraid of ignorant members of the public who will react out of fear and refuse to vaccinate their children.  The attempts at suppression however give rise to an equally plausible hypothesis as suggested by Dr. Healy ...  that Offit and company are afraid of what such inquiry might show.

NOTE: As the author of this blog comment I advise that my children have received all recommended and mandatory vaccines and that I have received vaccines at different times including during the H1N1 panic two years ago. I recognize the importance of vaccines in public health and safety. I am, however, seriously concerned about the incessant attempts to suppress scientific inquiry of vaccine safety issues and the view that all possible connections between vaccines and autism spectrum disorders have been explored and "debunked" for all time.  

Vaccines and Pregnancy: Lack of randomized, placebo-controlled trials and ... means ...?

My children have received their recommended vaccinations. I have had some although I am old enough that I received my measles and mumps shots the old fashioned way ... I had bad cases of both mumps and measles as a child.  I have not ... as yet ... attributed my son's autistic disorder to any injections he received, or that his mother received while carrying him, although I keep an open mind on the subject. I refuse to simply accept either  camp's dogmatic conclusions.

I believe that the public health authorities have shot themselves, no pun intended, in the foot with their dogmatic assertions that vaccines have "debunked" any vaccine autism connection and with their condescending, and at times pejorative and nasty, dismissal of parental observation, also known as direct, first hand observation, of changes in their children's conditions immediately following vaccinations. 

As one who has advocated strenuously for evidence based ABA treatment for autistic children I marvel at the ease with which some in the health sciences still do not accept ABA as an effective autism intervention after decades and hundreds of studies yet turn around and claim that a couple of dozen studies debunk all possible vaccine and vaccine ingredients even those given to pregnant women as possible causes or triggers of autism disorders.  I am amazed that some of the same people who claim that we can not know whether autism increases are real because of changed diagnostic definitions and social factors turn around and claim that epidemiological studies which fail to find a vaccine autism connection in some circumstances proves for all time that all possible vaccine autism connections have been dis-proven while ignoring for those purposes the changed diagnostic definitions and social awareness factors that complicated drawing safe conclusions.

Then there is the occasional study which does not seem to receive the usual attention of the NYT, the LAT or CNN perhaps because they are not so dogmatic in the debunking claims. The following abstract does not specifically mention autism disorders, (it might not get published if it did) but makes some interesting observations relative to the vaccine autism wars:


Authors: Makris, Marinos C.; Polyzos, Konstantinos A.; Mavros, Michael N.; Athanasiou, Stavros; Rafailidis, Petros I.; Falagas, Matthew E.
Source: Drug Safety, Volume 35, Number 1, 1 January 2012 , pp. 1-14(14)

Abstract:

Immunization during pregnancy has the potential to protect the mother and the newborn from preventable diseases. Current recommendations suggest that inactivated vaccines might be considered during pregnancy when the benefits outweigh the risks.

In this review, we aimed to evaluate the safety of hepatitis B (HB) vaccine, pneumococcal polysaccharide vaccine (PPSV) and meningococcal polysaccharide vaccine (MPSV) administration during pregnancy by systematically reviewing the available evidence in PubMed and Scopus databases, as well as postmarketing surveillance data (including the Vaccine Adverse Event Reporting System [VAERS] database). A total of 18 studies were eligible for inclusion in the review. Six studies provided data on HB vaccine, six on PPSV and three on MPSV; three additional studies compared PPSV with MPSV. Additionally, 91 reports on vaccinations of pregnant women were identified from postmarketing surveillance data (88 on HB vaccine, 2 on PPSV, 1 on MPSV). The most common complaints were local reactions, including tenderness and swelling. Overall, immunization during pregnancy did not seem to be associated with a teratogenic effect on the fetus, preterm labour or spontaneous abortion. However, the lack of randomized, placebo-controlled trials, or even large cohort studies, in addition to the inherent limitations of the reviewed observational studies with small statistical power, precluded safe conclusions. Large, prospective, population-based cohort studies are needed to elucidate this issue. (bold emphasis added -HLD)

The bold highlighted text states clearly that, at least for the vaccines listed in the study report title safe conclusions could not be drawn about the safety of those vaccines when given to pregnant women ... because of the lack of randomized, placebo-controlled trials, or even large cohort studies, in addition to the inherent limitations of the reviewed observational studies with small statistical power.  

Autism and the MMR Vaccine:Was Wakefield Confirmed by Wake Forest University School of Medicine Study?


UPDATE: The question in my comment title was answered, to some extent, by information passed to me that this study was reported in 2007. I have no idea why it shows up on the Daily Mail online with today's date at the top of the page and with no internal story dates to indicate it is not current. It also shows up in Google News.  


I did a web search by the author's name and found the same article published in different places on the web on different dates. What I haven't found is what happened to the Wake Forest study?  If anyone knows feel free to offer your information. HLD


According to a report in the UK Daily Mail, Scientists fear MMR link to autism,  a study led by Dr. Stephen Walker of  the Wake Forest University School of Medicine in North Carolina appears to confirm findings in the much maligned 1998 study by Dr. Andrew Wakefield. The research team are examining 275 children with regressive autism and bowel disease and,  of 82 tested so far,  70 prove positive for the vaccine strain, not the wild strain, of the measles virus. The report also indicates that the this is the second study including the O'Leary 2001 study to confirm the Wakefield findings:

"Last night the team's leader, Dr Stephen Walker, said: 'Of the handful of results we have in so far, all are vaccine strain and none are wild measles.

'This research proves that in the gastrointestinal tract of a number of children who have been diagnosed with regressive autism, there is evidence of measles virus.

'What it means is that the study done earlier by Dr Wakefield and published in 1998 is correct. That study didn’t draw any conclusions about specifically what it means to find measles virus in the gut, but the implication is it may be coming from the MMR vaccine. If that’s the case, and this live virus is residing in the gastrointestinal tract of some children, and then they have GI inflammation and other problems, it may be related to the MMR.'

The 1998 study by Dr Wakefield, then a reader in gastroenterology at the Royal Free Hospital in North London, and 12 other doctors claimed to have found a new bowel disease, autism enterocolitis.

At the time, Dr Wakefield said that although they had not proved a link between MMR (measles, mumps, rubella) and autism, there was cause for concern and the Government should offer the option single vaccines - instead of only MMRs - until more research had been done.

The paper - and the confused interpretation of its findings - caused uproar and led to many parents withdrawing their co-operation for the triple jab. Ten of the paper's authors also signed retractions on the interpretation but stood by the science.

This is the second independent study to back up Dr Wakefield. In 2001 John O'Leary, Professor of Pathology at St James's Hospital and Trinity College, Dublin, replicated his findings.

Last night Dr Wakefield said: 'This new study confirms what we found in British children and again with Professor O'Leary. The only exposure these children have had to measles is through the MMR vaccine.

'They were developing normally until they regressed. They now suffer autism and bowel disease."'The Department of Health and some of the media wanted to dismiss our research as insignificant. The excuse was that no one else had the same findings as us. What they didn't say is that no one else had looked."

This study will be subjected to very close scrutiny.  Not just because it might implicate vaccines in some instances of autism, and should be examined closely as part of the scientific method,  but also because a war has been waged on Dr. Andrew Wakefield.  Those who have waged that war have much to lose if the information reported by the Daily Mail is confirmed.  Their own reputations are now on the line. They  can not,  and will not,  accept any study or information which calls into question their efforts to discredit Wakefield and his study. 

Study Finds Positive Association Between Autism and Vaccines


A  recent (Online publication date: 26 May 2011) study published in the Journal of Toxicology and Environmental Health reports ,as set out in the report title, that a positive association has been found between autism and vaccines: A Positive Association found between Autism Prevalence and Childhood Vaccination uptake across the U.S. Population. The study abstract places the conclusion in the context of current thinking which sees autism as the interaction of genetic predispositions and environmental triggers.  It also identifies flaws in some of the major studies which are touted as "debunking" any possible autism vaccine connection.

The genetic-environmental model of autism causation does not appear to have broken through the rigid mindsets of  those who sek to discourage  any further investigation of possible autism vaccine connections, people like  Paul Offit, Bill Gates and Richard Gorski.  These attack dogs will undoubtedly bark and snarl at this study and attack personally anyone involved with it.

For people with open minds on this serious issue though the article abstract states:

"One of those triggers might be the battery of vaccinations that young children receive. Using regression analysis and controlling for family income and ethnicity, the relationship between the proportion of children who received the recommended vaccines by age 2 years and the prevalence of autism (AUT) or speech or language impairment (SLI) in each U.S. state from 2001 and 2007 was determined. A positive and statistically significant relationship was found: The higher the proportion of children receiving recommended vaccinations, the higher was the prevalence of AUT or SLI. A 1% increase in vaccination was associated with an additional 680 children having AUT or SLI. Neither parental behavior nor access to care affected the results, since vaccination proportions were not significantly related (statistically) to any other disability or to the number of pediatricians in a U.S. state. The results suggest that although mercury has been removed from many vaccines, other culprits may link vaccines to autism. Further study into the relationship between vaccines and autism is warranted."


This study, like all studies, including those that purport to "debunk" any autism vaccine connections will, and should, be given close examination, and criticism, if warranted.  Hopefully reviews of this study will be conducted by serious, objective scientists and not just those with a "defend vaccines at all costs" agenda.  That, of course, is a very faint hope.  Paul Offit and his followers have doubled down on the irrational strategy of personally attacking parents, and researchers, concerned about possible role of vaccines and vaccine ingredients in triggering autism and other neurological disorders in children instead of continuing calmly with objective examination of their concerns.  

Wheeling & Dealing & Avoiding FDA Scrutiny at the Vaccine Business Industry (Big Pharma) Congress



The vaccine industry business congress  referenced above states that it is scheduled for Baltimore in the fall of 2011 although the agenda indicates dates in March 2011.   More significantly the first items on the agenda show clearly the priorities of Big Pharma, as the conference brochure itself refers to the vaccine industry, which are maximizing government sponsored funding and avoiding FDA scrutiny.  Great stuff.

Yes, the Congress brochure does refer, several times, to Big Pharma, so don't go all Orac berserk on me for using that expression.

No word on whether  Offit, Orac, Mnookin or Deer were/will be in attendance.

Blame Game: Health Officials Blame Their Vaccine Program Failures on Autism Concerned Parents


The past 2 years have seen an onslaught of attacks on anyone who raises any questions about vaccine safety and in particular against anyone who suggests that vaccines might be implicated in causing or triggering autism disorders in some children.  Dr. Paul Offit has been the New York Times go to guy in promoting vaccine programs for almost a decade. His crusade to prevent discussion of possible autism vaccine connections was kick started with his New York Times Op-Ed "contribution" in March 2008 criticizing the results of the Hannah Poling case. 

With that opinion Dr. Offit expanded his unquestioned status as a vaccine expert to include his self appointed/self anointed status as an autism expert AND as a legal expert. The Offit Offensive began in full force in January 2009 with the New York Times' ceaseless coverage of  Offit's False Prophets and his drive to shut down discussion of vaccine safety issues.  The criticism of those who raise autism and safety issues has intensified with the ceaseless attacks on Dr. Andrew Wakefield and the unproven fraud allegation of the  BMJ (after the fact admitter of conflicts) and its adoptee  Brian Deer.

The result of the Offit Offensive? After years of attacking vaccine questioners public health authorities continue to see declines in vaccination rates and continue to blame those who question vaccine safety particularly those who are concerned about possible vaccine autism connections.  In just the most recent example in the news Minnesota doctors and health authorities are again tying declining measles vaccination rates and increased measles outbreaks to "erroneous" allegations of vaccine autism connections. 

As the parent of fully vaccinated sons I have never blamed vaccines for my younger son's autistic disorder and profound developmental delays.  I myself receive vaccines when I think them necessary or when advised by my family doctor. I believe vaccines to be important public health tools but like all of man's inventions I do not believe that they are  flawless.  Vaccines have caused injury in the past.  That is fact and it is reasonable for people to ask questions about the safety of vaccines.  The anecdotal evidence of vaccine autism connections, even acknowledging the weakness of anecdotal evidence, can not be ignored unless and until strong studies are done to convince parents that what they believe they have seen is not what really caused their children to lapse into a serious neurological disordered condition.  Failure to persuade the public is the failure of the health authorities and the persuasion strategies they have adopted to promote vaccine safety.  Decline in public confidence in vaccines is the failure of the health authorities not the public they are trying to convince.

While portrayed as being a front line crusader for the safety of children by vaccination Dr. Paul Offit is not in fact on the front lines.  It is parents who are on the front  lines fighting for their children's well being and health day in an day out. Calling them ignorant or irrational won't win their hearts and minds.  Blaming them for the decline in vaccination rates in some areas will not win the day for vaccine programs. Solid, credible studies free of pharmaceutical company influence by credible, trusted research authorities will. 

Will New Prohibition Against Exploring Possible Vaccine Autism Connections Stop ALL Environmental Autism Research?


The last few years have seen an all out offensive to shut down discussion of vaccines as possible triggers of autism disorders.  The withdrawal of the 1998 Lancet article, the banishment of Dr. Andrew Wakefield by British medical authorities, the conviction of Andrew Wakefield of fraud in The Court of Brian Deer and the mainstream media puppeting and promotion of the Deer conclusions have occupied much public space in discussion of autism disorders.  And of course no less a public figure than Bill Gates has accused those who question vaccine safety of killing children around the globe. Autism Speaks has declared that it "is time to change the conversation".  In other words "sssshhhhhhhhhhhhhhhuuuuuttttttt up" or face the consequences.

In the era of the New Prohibition, the prohibition against discussion of  possible vaccine autism discussions, will research which MIGHT implicate vaccines as possible be prohibited? Environmental autism research focused on prenatal and early postnatal environmental impacts on the fetus and developmental disruption has been featured in reports to the US senate on the State of Research on Potential Environmental Health Factors with Autism and Related Neurodevelopment Disorders:

Paul Anastas Ph.D. Assistant Administrator for Research and Development and Science Advisor U.S. Environmental Protection Agency (EPA)


Because of its extraordinary complexity, prenatal and early postnatal brain and nervous system development can be disrupted by environmental exposures at much lower levels than would affect adults.5,6,7,8,9 We are learning that there are critical windows of susceptibility both prenatally and in early childhood, during which the effects of exposures to environmental contaminants, depending on dose and timing, can be significantly more severe and can lead to permanent and irreversible disability.10,11,12 For these and many other reasons, EPA is especially concerned about potential effects of environmental chemicals on children’s health and neurodevelopment.

Linda Birnbaum, Ph.D., D.A.B.T., A.T.S. Director, National Institute of Environmental and Health Sciences and National Toxicology Program National Institutes of Health, United States Department of Health and Human Services

Development of the nervous system begins in the womb and extends through childhood. During these periods of rapid development, the brain is vulnerable to some environmental exposures that may have the potential to disrupt the chemical signals that organize development. Even small changes in the timing of critical development events can potentially have major consequences for brain structure and function. Thus even brief exposures at these vulnerable stages can have lasting effects on adult brain function. We refer to "windows of susceptibility: to mean the life stage at which the brain is exposed, during which different agents can effect the brain in specific and deleterious ways. For example, the dose of lead that is neurotoxic to an infant is much less than the dose that would be neurotoxic for an adult, so infancy in this case is a "window of susceptibility" .... Learning disabilities are on the rise in the United States and we now have a significant body of information on how exposure to certain environmental agents can affect children's intelligence quotients (IQs). For example, scientific literature attests to the effect of lead exposure in early life on IQ. ... Mercury also has been shown in multiple studies to be a developmental neurotoxicant. .... A study published last year from Columbia University showed that a mother's exposure to urban air pollutants known as polycyclic aromatic hydrocarbons (PAHs) can adversely affect a child's IQ.  PAHs are released into the air from the burning of coal, diesel, oil, gas and other organic substances such as tobacco.  In urban areas motor vehicles are a major source of PAHs. 

Bruce P. Lanphear MD, MPH Senior Scientist, Child & Family Research Institute, Professor, Simon Fraser University, Vancouver, BC, Adjunct Professor, Cincinnati Children's Hospital Medical Center


Children’s environmental health -- the study and prevention of disease and disabilities in children from exposures to social, physical, biologic, and chemical agents -- has emerged as a new field of research, policy, and clinical practice (Landrigan et al. 1998). The growth of this field has been fueled by the emergence of new morbidities in children, research showing that the fetus and child are particularly vulnerable to environmental influences, and mounting evidence implicating environmental exposures as major risk factors for prevalent diseases and disabilities in children (Lanphear, 2005).


One in six American children have a developmental problem, from a subtle learning disability to overt behavioral disorders, such as attention deficit hyperactivity disorder (ADHD) or autism (Boyle et al. 1994; Hertz-Picciotto, 2009). These conditions can severely impair a child’s ability to succeed in school, elevate their risk for violent and criminal behaviors, and dramatically diminish their ability to contribute to society. The findings from some of the most thoroughly studied and widely dispersed environmental toxicants indicate that exposure to exceedingly low levels are risk factors for the “new morbidities” of childhood -- intellectual impairments, behavioral problems, asthma and preterm birth (Lanphear, 2005). Indeed, there is often no apparent threshold and, in some cases the effects appear to be greater at the lowest levels of exposure (England et al. 2001; Canfield et al. 2003; Lanphear et al. 2005; Yolton et al. 2005).

Exposures to established environmental toxicants -- such as lead, tobacco, PCBs and mercury -- have consistently been linked with higher rates of intellectual impairment or behavioral problems, such as conduct disorder and ADHD (Needleman et al. 1990; Schantz et al. 2003; Kahn et al. 2003; Wakschlag et al. 2002; Stewart et al. 2003; Needleman et al. 1979; Lanphear et al. 2005; Yolton et al. 2005). There is emerging evidence that a whole host of new environmental chemicals – such as Bisphenol A, PBDEs, pesticides, phthalates, and airborne pollutants – are associated with intellectual deficits or behavioral problems in children, but the evidence is not as conclusive (Rauh, 2006; Engel, 2010; Eskenazi, 2007; Braun, 2009; Perera 2009; Herbstman, 2010). Much of this research was done by the NIEHS/US EPA Children’s Environmental Health Research Centers working collaboratively with the Centers for Disease Control and Prevention.


Children’s developing brains are more vulnerable to certain toxicants and pollutants than adults. The central nervous systems of the fetus and young child, which are undergoing rapid changes, are particularly vulnerable to some toxicants. The fetus is a recipient of toxicants through placental transfer (Perera et al. 2003; Whyatt and Perera 1995; Bearer 2003). In some cases, such as mercury, the fetus is exposed to a larger dose than the mother (Ramirez et al. 2000). In other cases, such as organophosphate pesticides, the fetus may lack critical enzymes to metabolize environmental toxicants (Chen et al. 2003). Toddlers are often at greater risk for exposure to many environmental toxicants because they have a high degree of hand-to-mouth activity and they absorb some toxicants more efficiently (Bearer 1995).

As the above quotes illustrate environmental  research is examining many potential causes and triggers of autism disorders at the prenatal and early childhood stages.  Mercury is only one of the potential causes of autism being researched but it is one which is very sensitive to those who insist that discussion and research of possible vaccine autism issues must stop.   Teresa Binstock wrote about the "it's gotta be genetic" model of autism and the consequences for any professional who explored vaccine autism connections over a decade ago.   Much of what Binstock discussed is taking place now as Dr. Andrew Wakefield is well aware.  The current suppression of vaccine safety discussion and research will probably be accompanied by a complete return to the 100% genetic model of autism, a model which has already sucked the life out of environmental autism research funding for decades.  All serious efforts to find the environmental causes of the vaccine epidemic, to find out what is really happening to  our children are likely to come to an end.

Autism Vaccine War: Will the Bill Gates Posse Go After the IACC and the IOM?



The following paragraph is taken directly from the IACC, the United States Interagency Autism Coordinating Committee , web site as of February 15 2011.  The only change is the bold highlighting of the last two sentences which I added for emphasis and which clearly contradicts the aggressively promoted opinion that science has conclusively ruled out a link between vaccines and autism disorders.

"Progress in identifying environmental factors which increase autism risk has been made recently (Eskenazi et al., 2007; Palmer et al., 2006; Palmer, Blanchard, & Wood, 2009; Rauh et al., 2006; Roberts et al., 2007; Windham et al., 2006), although this area of research has received less scientific attention and far fewer research dollars than genetic risk factors. Environmental factors may be pertinent not only to brain development but also to chronic systemic features of at least some subgroups of ASD. An Institute of Medicine (IOM) workshop held in 2007 summarized what is known and what is needed in this field (Forum on Neuroscience and Nervous System Disorders, Institute of Medicine, 2008). Numerous epidemiological studies have found no relationship between ASD and vaccines containing the mercury based preservative, thimerosal (Immunization Safety Review Committee, 2004). These data, as well as subsequent research, indicate that the link between autism and vaccines is unsupported by the epidemiological research literature. However, the IOM report acknowledged that the existing population-based studies were limited in their ability to detect small susceptible subpopulations that could be more genetically vulnerable to environmental exposures."

Of course the smallest susceptible subpopulation is always an individual.  And apart from any person with a specific genetic predisposition children before and shortly after birth are always vulnerable. They are always susceptible to the impact of environmental factors.  The IACC acknowledgement, as I read it, does not mean that possible vaccine autism links are "debunked" for all time or that the "science" is closed on the matter. Former CDC Directors Dr. Bernadine Healy and Dr. Julie Gerberding (now with Merck) have both previously stated that a comparative study of autism rates in existing vaccinated and non vaccinated populations could and should be done. Has a vaccine autism link been proven? Not as far as I am aware reading materials such as that on the IACC web site.  Is the science closed on possible vaccine autism links? Not as far as I can tell when reading IACC information which states that the studies which did not find links were "LIMITED".

IMPORTANT NOTE FOR THE BILL GATES POSSE: I am a father of two sons both of whom are fully vaccinated and I have received vaccines myself including the H1N1 Swine Flu shot.  I have never attributed my younger son's Autistic Disorder to vaccine injury.  I believe that vaccines are very important, but not perfect,  public health tools which are strengthened as public health tools by continuing to ask questions about their safety and by treating parents and professionals who ask such questions with respect.  I believe that your current attacks on parents and professionals who ask questions about vaccine safety and autism and your wild eyed allegations of lies and homicide will be counterproductive in any effort to restore public confidence in vaccines.  

Failing and Flailing The Current Pro Vaccine Campaign Promotes New Autism Myths



It appears that those who promote vaccines as an important  public health tool are losing their battle to persuade people that vaccines are perfectly safe and do not cause any harm, do not cause neurological damage and do not  cause or trigger any of the neurological disorders in any children ever.  I say this as the father of two children who have received all required and recommended vaccines. I say this as the father of a 15 year old son  with Autistic Disorder and profound developmental delays who has never attributed his son's disorders to vaccine injury.  I say this as a person who believes that vaccines are in fact an important, but not a perfect,  public health tool. I say this as a person who believes that Bill Gates' screaming and  frothing from the corners of his mouth while yelling murder, murder at the top of his lungs will not work.  I believe that the current strategy of attack will not work, will be counterproductive and will result in further declines in vaccination rates.

I say this because I believe that those who engage in such attacks have failed, utterly failed to demonstrate any knowledge or understanding of autism disorders or the challenges faced by the parents they belittle and denigrate directly and by implication with their simplistic allegations.  I believe that those who continue these unproductive strategies should themselves accept responsibility for declines in vaccination rates.  They have failed and now they flail. They flail wildly and continue their failure and quite possible increase the numbers of persons who will now be suspicious of vaccine safety.

The current offensive against those who ask any questions about vaccine safety has gone from alleging poor research, to making unproven in a court of law allegations of fraud and homicide.  The research of one journalist forms the basis of a world wide big media stream of allegations of fraud against Dr. Andrew Wakefield.  The bases for Bill Gates wild eyed claims that those who question vaccine safety are responsible for killing children is not articulated anywhere in any comprehensible form.  New autism myths are created and one of the myths that demonstrate the ignorance of those who promote vaccines at any cost is the myth that large sums of autism research dollars have been diverted from finding causes of autism disorders to proving that vaccines do not cause autism.

At Medical News Today Christian Nordqvist (Editor in Chief and CEO of Medical News Today) confesses in The Tragedy Of The Fraudulent MMR Autism Link, A Personal Story    that he once had nagging doubts about whether his son's Asperger's Syndrome was caused or at least aggravated by receipt of an MMR vaccine.  Now he is satisfied beyond all doubt, after reading the Brian Deer "research" alleging fraud against Dr. Wakefield that the MMR vaccine played no role in his son's conditions.   There is not much substance in Mr. Nordqvist's recounting of his struggles with his nagging doubts but there is one glaring and false autism myth which the Editor in Chief and CEO of Medical News Today is quite happy to promote when he states:

The billions of dollars, Euros, Pounds and Yens that did not go into autism research between 1998 and today, because philanthropists, grant givers and government departments might have been distracted by these false findings, now need to go into autism research. We do not know whether a huge grant might have occurred during this period that would have achieved a massive breakthrough in this field if that study had not been published - if so, I name it a tragedy for babies with autism born yesterday, today and in the near future, and also for their parents, siblings and other close relatives.


(Underlining added HLD)

That is one of the biggest reaches that I have yet seen in the debates about autism and autism research.  Mr. Nordqvist starts by stating that "billions of dollars, Euros etc" did not go into autism research beteween 1998 and today"  because potential sources of research dollars MIGHT have been distract by what he calls Wakefields false findings.   No evidence, study, research or source of any kind is referenced to support this wild speculation.  Mr. Nordqvist is happy to then go on and speculate about all the autism research that might have resulted in a massive breakthrough had the Wakefield study not been published.


Might, might, maybe, ah ha! pretty well sums up Mr. Nordqvist's sorry logic.

OK, the article by the editor in chief and CEO of Medical News Today might be the weakest and loopiest of all the comments made in the heated vaccine autism wars but it does show clearly the depths to which  those who seek to silence anyone who questions vaccine safety will descend. 

Will Current Media Frenzy Attacking Possible Autism Vaccine Links Be Counter Productive?


Will the current media frenzy unleashed with the BMJ-Brian Deer fraud allegations (unproven in a court of law) against Andrew Wakefield, followed up with another Paul Offit big media tour, and a star celebrity turn by Bill Gates yelling "LIARS" in his very loud voice finally result in an increase in vaccinations or will it be counterproductive?    Feel free to register your vote on the poll at the top of the sidebar. 

Should Wakefield Be Prosecuted as "Special to CNN" Commentator Advocates?



Alex B. Berezow, according to the CNN Opinion site, is the editor of RealClearScience and holds a Ph.D. in microbiology.  Mr. Berezow has provided a "special to CNN" opinion in which he argues that Dr. Andrew Wakefield should face  criminal prosecution for fraud in the United Kingdom AND in the United States. Alex B. Berezow Ph.D. repeats the accusation published in the BMJ that Wakefield falisfied patient histories in the now retracted Lancet study.  

Berezow leaves no doubt that, in his mind, Wakefield is guilty of fraud:

"It is for these reasons that Wakefield should be prosecuted to the fullest extent of American and British law. Perhaps if he spends the next few years behind bars, people who have suffered from the impact of his actions will see that justice is being done."

Berezow does not consider the other possibility, the possibility that Wakefield is NOT guilty of fraud.  This humble small town Canadian lawyer lacks the intellectual brilliance of a microbiologist and CNN commentator, and lacks the ability to get past, as the mainstream media appears to have done,  that old fashioned "presumption of innocence" thing. 

It is not my place to tell authorities in any jurisdiction who they should prosecute, or for what alleged offences.  I do not advocate that Dr Wakefield should face prosecution based on the work of journalist Brian Deer or any journal publication.  If a prosecution does take place though,  as Mr Berezow desires, it would, at least, give Dr. Wakefield an opportunity to answer the allegations. At this time the fraud allegations, remain just that ... allegations, notwithstanding the massive media piling on and promotion of those allegations as though they were proven facts.

Will a fraud prosecution happen?  Or will unproven fraud allegations continue to be made with abandon in the mainstream media?  Dr. Wakefield would obviously lose much if convicted.  But the credibility of the BMJ, the Mainstream Media and Brian Berezow would suffer greatly if Dr Wakefield was acquitted or found NOT GUILTY.

I am going to guess wildly that no prosecution will occur, that those who allege Wakefield committed fraud  are happy to let the Mainstream Media repeat the allegations as fact and let it end at that.

Autism Rising: CDC Says Autism Increase is Real

One of the heated  debates, of the many, that arise in discussion of autism related matters is whether the rates of autism increase is real, in whole  or in part, or whether the rates are increasing solely because of 1994 diagnostic definition changes in the DSM and increased social awareness.  The  United States Center for Disease Control however, in arguing that thimerosal, the mercury contained in some vaccines, does not cause autism disorders, has taken the clear and unambiguous position that increasing numbers of autism diagnoses reflect a real increase in autism disorders:

"Does thimerosal cause autism?

Research does not show any link between thimerosal in vaccines and autism, a neurodevelopmental disorder. Although thimerosal was taken out of childhood vaccines in 2001, autism rates have gone up, which is the opposite of what would be expected if thimerosal caused autism."
Obviously if the increases in autism diagnoses did not reflect real increases in autism there would be no merit to the CDC position that increased autism rates confirm that thimerosal does not cause autism.   The increases in autism diagnoses are real, autism IS rising, the CDC says so.

Where Is the Evidence that Celebrity Autism Advocates are Causing Drop in Vaccination Rates?

Whenever information surfaces showing a drop in vaccination groups in any geographic area or social demographic group the media and public health authorities blame celebrity autism advocates for the drop. TIME magazine does exactly that in commenting on the National Committee for Quality Assurance (NCQA) Report indicating   that a drop in vaccination rates is occurring amongst children of wealthier parents while rates  actually increased amongst children of poorer parents.


Wealthier families, meantime, are getting too much of their health advice not from doctors and epidemiologists, but from talk shows, the blogosphere and the rumor mill, all of which are filled with vaccine scare stories. Making things worse is that the kind of folks spreading the tales are precisely the kind we find hardest to ignore.

"Very articulate, very good-looking movie stars or personalities ... are giving out information about how bad vaccines are," pediatrician Robert Frenck of the Cincinnati Children's Medical Center told the online health news service HealthDay. "Frumpy middle-aged doctors" find it awfully hard to compete with that.
   
The NCQA web site in a news releaase titled NCQA REPORT: QUALITY, SPENDING NOT LINKED; AUTISM FEARS SUSPECTED AS CHILDREN'S VACCINATIONS DECREASE IN PRIVATE PLANS states:

"Childhood vaccination rates in 2009 declined by almost four percentage points in commercial plans.

A possible cause of this drop is commercial plan parents may refuse vaccines for their children based on the unproven, but increasingly popular, notion that vaccines cause autism. Celebrity activists are outspoken advocates of this view. Interestingly, we see vaccination rates in Medicaid – the program serving the poor – continuing to steadily improve.

“The drop in childhood vaccinations is disturbing because parents are rejecting valuable treatment based on misinformation,” said NCQA President Margaret E. O’Kane. “All of us in health care need to work together to get better information to the public."

Neither  the TIME Magazine article, nor the NCQA news release, reference any studies which provide evidence that the drop in vaccination rates amongst children of wealthier parents is due entirely, or in part, to celebrity autism advocates and bloggers ....  good looking or not.

Insulting parents of autistic children (and celebrities) has not worked to restore confidence in parents that vaccines are safe generally or that they are NEVER involved in causing autism in ANY cases even amongst children of women injected with mercury containing vaccines while they were pregnant. I have commented previously (1) (2) on the insanity of continuing with this failed strategy while hoping for a different outcome yet the NCQA and TIME continue to do so.

Unlike the intellects at TIME and NCQA I will not assume that they will ever learn their lesson. I do not expect public health authorities, or TIME, to learn that maybe it is time to start treating the public with respect and make their case with solid, credible studies both as to the cause of drops in vaccination rates and on whether vaccines contribute to autism or any other disorders. Former NIH Director Dr. Bernadine Healey has stated that comparative studies comparing autism rates amongst vaccinated and existing unvaccinated populations should be done but no such study has been attempted. Instead excuses are offered by public health authorities who continue to dismiss, and attack, anyone who asks questions about the efficacy or the safety of vaccines.

There is no evidence that TIME or public health authorities will ever change their view of the public as ignorant, unwashed and incapable of understanding serious issues. It appears to be far easier for public health authorities to blame the public, or good looking high profile members of the public, than to convincingly demonstrate the safety and efficacy of vaccines.

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